CD28 and autoimmune hepatitis: In addition, we discovered that there are two immunophenotypes that have dangerous effects on AIH:CD28-CD8+ T cell %CD8+ T cell (OR = 2.203, 95%CI 1.457 ~ 3.331, p = 0.00018, PFDR = 0.028), CD28-CD8+ T cell Absolute Count (OR = 2.354, 95%CI 1.587 ~ 3.493, p = 2.107 × 10−5, PFDR = 0.0097).