However, in addition to being a potential target for CAR-T Cell therapies (Li et al. 2022), the expression levels of RAB3B influence the progression of gliomas (Luo et al. 2021), metastasis and chemoresistance in cancer stem-like sphere cells from a human hepatoma cell line (Tsunedomi et al. 2022). The gene discussed is RAB3B; the disease is hepatocellular carcinoma.