While RAB6B has been linked to poor prognosis in breast cancer patients (van’t Veer et al. 2002), it is also a promising prognostic marker of hepatocellular carcinoma (Peng et al. 2022), and further in vitro studies are needed to explore its prognostic potential in renal metastasis as per our results. This evidence concerns the gene RAB6B and breast carcinoma.