TTR and monoclonal gammopathy: Given monoclonal gammopathy, clinicians may infer that AL amyloidosis is the diagnosis; however, “Occam's Razor” can be misleading, particularly in Black individuals, among whom monoclonal gammopathies occur at twice the rate observed in white individuals, while mutated TTR genes are present in 3.9% of Black individuals, especially the p.Val122Ile (V122I) mutation (4).