The results showed that most of the lipid molecules including LDL-C, LDL: High density lipoprotein (HDL) ratio, non-HDL, apolipoprotein (Apo) A1, Apo B and PCSK9 levels were lower in SLE patients than in controls, with the exception of HDL cholesterol. The gene discussed is PCSK9; the disease is systemic lupus erythematosus.