Transcripts of PGRPs are expressed in insect tissues known to play a role in the immune response (e.g., hemocytes, fat body, and midgut); however, their upregulation in response to bacterial infection is variable, with many long PGRP (PGRP-L) genes constitutively expressed in certain immune tissues [39]. The gene discussed is PGLYRP2; the disease is bacterial infectious disease.