The exclusion criteria were as follows: 1) patients with cerebral infarction sequelae and modified rankin scale (mRS) ≥ 1; 2) suffering from severe underlying diseases; 3) patients with stroke mimics; 4) missing mRS data; 5) patients without eGFR, WBC count, and CRP data collected within 4.5 h of symptoms of stroke onset. This evidence concerns the gene CRP and Stroke.