Observing increased IFNγ-induced PD-L1 expression in the dedifferentiated 624Mel cells is partly in line with previous studies where SOX10 knockdown, which reduces MITF expression in melanoma cells, led to increased IFNγ-induced PD-L1 expression in three out of four tested melanoma cell lines[21]. The gene discussed is SOX10; the disease is melanoma.