CD274 and metastatic neoplasm: In univariable Cox regression analysis, higher age, chemoimmunotherapy treatment (compared with monoimmunotherapy), higher stage of clinical stage metastatic disease (compared with cM1a), PD-L1 TPS less than 1% (compared with PD-L1 TPS ≥ 50%), and KRASwt/TP53wt or KRASmut/TP53wt status (compared with KRASmut/TP53mut) were associated with shorter OS.