For instance, the causal relationships between PPAR activity and the various biological aspects that collectively influence cancer development and treatment response in TNBC, such as the expression of identified oncogenic genes and signaling pathways, antitumor immune-related molecules and pathways, infiltration of antitumor cells, abundance of specific microorganisms, and expression of certain chemoresistance-related genes, need further clarification. Here, PPARA is linked to cancer.