Specifically, higher-grade tumors in PAAD, HNSC, Glioblastoma Multiforme (GBM), Lower-Grade Glioma (LGG), and LIHC exhibited elevated HNRNPC expression levels, while in KIPAN and KIRC, higher expression levels were associated with lower-grade tumors. The gene discussed is HNRNPC; the disease is glioblastoma.