FZD4 and posterior cortical atrophy: The results from luciferase reporter assay revealed that treatment with the miR-24-3p mimics led to a marked decrease in the luciferase activity of the wild-type FZD4/5 (FZD4/5-wt) reporter, whereas the activities of the mutated FZD4/5 reporters were unchanged in PCa cells with miR-24-3p mimics treatment (Figures 5E, F).