Physical activity boosts brain-derived neurotrophic factor (BDNF), promoting neuroplasticity (Loprinzi and Frith, 2019), and consequently enhancing memory and learning (Piepmeier and Etnier, 2015), while also offering protection against Alzheimer’s and depression (Bjornebekk et al., 2005; Erickson et al., 2011; Liu and Nusslock, 2018). This evidence concerns the gene BDNF and depressive symptom measurement.