In sepsis, Univariate logistic regression analysis showed significant differences in musculoskeletal or connective tissue diseases (OR 3.512, 95% CI 1.372–8.988, p = 0.009), CRP (OR 1.008, 95% CI 1.003–1.013, p = 0.002), albumin (OR 0.546, 95% CI 0.315–0.944, p = 0.03), tracheal intubation (OR 5.108, 95% CI 1.151–22.670, p = 0.032). The gene discussed is ALB; the disease is Sepsis.