The IVW genetic prediction method revealed the presence of elevated levels of Eotaxin (CCL11) (OR = 1.164, 95% CI 1.034–1.311, P = 0.012), Monocyte chemoattractant protein-4 (CCL13) (OR = 1.131, 95% CI 1.034–1.238, P = 0.007), Matrix metalloproteinase-10 (MMP-10) (OR = 1.129, 95% CI 1.015–1.257, P = 0.026), Signaling lymphocytic activation molecule (SLAMF1) (OR =, 95% CI 1.015–1.257, P = 0.026) and Tumor necrosis factor ligand superfamily member 14 (TNFSF14) (OR = 1.219, 95% CI 1.086–1.369, P = 0.001) were associated with an increased risk of dry AMD. The gene discussed is SLAMF1; the disease is dry age related macular degeneration.