In the integrative and comparative analysis of DEGs in the dataset of BCP-treated HepG2 cells with the TCGA-LIHC dataset from liver cancer patients, we discovered BCP-mediated alterations of five MAPK signaling pathway-related genes, including upregulated NR4A1 and CSF1R and downregulated PGF, ARTN and CACNA1E. Here, NR4A1 is linked to liver cancer.