Cox regression proved that TMM status, in particular ALT activation, had a significant predictive value of event-free survival in non-stage 4 patients, independent of age at diagnosis, sex, tumor histopathology and ploidy, using both stepwise forward (HR = 5.52, p < 0.001, CI = 2.5-12.0) and backward Wald methods (HR = 2.86, p = 0.04, CI = 1.1-7.8). Here, GPT is linked to neoplasm.