The results showed that both 5‐FU+JQ1 and 5‐FU+C297 significantly inhibited tumor growth, leading to smaller tumors and slower tumor growth (Figure 7A–C,F–H), and fewer Ki‐67 positive cells compared with 5‐FU alone (Figure 7E; Figure S14, Supporting Information). This evidence concerns the gene MKI67 and neoplasm.