Low expression of ARHGEF10L in CD14 + monocytes is associated with increased death from sepsis (Liepelt et al. 2020), and the list included genes related to anti-bacterial activity (LCN2) (Flo et al. 2004), regulation of TLR4 responses (SLC15A3) (Song et al. 2018), LPS sensitivity and autophagy (RUBCNL and SLC8A1) (Zi et al. 2015; Neubert et al. 2020) and apoptosis (FAS, TNFRSF21, TNFRSF8) (Dostert et al. 2019). The gene discussed is TLR4; the disease is Sepsis.