Among these, 10 genes, CAV3, DSG2, LDB3, LMNA, MYBPC3, MYLK2, SCN5A, TCAP, TTN, and TTR, have been defined as the associated genes of cardiomyopathy by the 2023 European Society of Cardiology (ESC) Guidelines [27]. The gene discussed is DSG2; the disease is cardiomyopathy.