(F) Occupancy of TRF2 by ChIP-qPCR at the IL1R1 promoter spanning +200 to –1000 bp of TSS was reduced in xenograft tumours made from HT1080 cells with long telomeres (HL1080-LT) relative to ones with short telomeres (HT1080) cells (N=3 in each case; IL1R1-3’UTR or a region 20 kb upstream were used as negative controls for TRF2 binding). The gene discussed is IL1R1; the disease is neoplasm.