However, given the known linkage disequilibrium between DQB1*05, DRB1*16 and DRB1*14, along with the higher statistical significance of the associations with the last two alleles and the fact that HLA-DQ*05 frequency among myasthenic patients in our study (42.30%) was lower than in other studies (73% in Italian MuSK+MG patients, 78.3% in Dutch MuSK+MG patients and 42.60% in Italian LOMG patients), it is possible that HLA-DQ*05 is not actually a susceptibility marker for MG in our group of Romanian patients [16,18,19]. Here, HLA-DRB1 is linked to myasthenia gravis.