METTL14 and Abnormal retinal morphology: Although previous work has demonstrated that Mettl14 is indispensable for both photoreceptor cell function and survival, elucidation of the function of Mettl3, as the only catalytically active key protein in the methyltransferase complex, in photoreceptor cells can further stress the importance of m6A modification in visual maintenance and provide theoretical support for subsequent treatment of retinal diseases.