1. Offspring prenatally exposed to DBP + streptozotocin showed an increase in blood glucose concentration and a decrease in insulin levels2. FoxM1 expression levels were decreased due to its negative regulation by the phosphorylation of STAT1 (pSTAT1), which showed high expression levels3. The abnormal regulation of pSTAT1 and FoxM1 resulting from exposure to DBP is fundamental to the development of gestational diabetes mellitus. The gene discussed is STAT1; the disease is gestational diabetes.