TGFB1 and renal fibrosis: 1. Decreased size of the fibrotic kidneys of the offspring with thickening of the tubular basement membrane and tubular damage2. Increased expression of TGF-β13. Maternal exposure to DBP promotes Snail1-mediated epithelial–mesenchymal transition through up-regulation of TGF-β1, leading to the development of renal fibrosis