GDNF and renal dysplasia: 1. Reduced expression of genes involved in kidney development (Foxd1, Wnt11, Pax2, Gdnf), while increased expression of genes related to kidney structure (Bmp4, Cdh11, Ywhab, Calm1), suggesting that exposure to DBP can lead to incomplete kidney development 2. Increased expression of α-SMA proteins, fibronectin and TGF- β3. Maternal exposure to DBP can induce renal dysplasia in PND1 and renal fibrosis in adulthood