1. Decrease in maternal body weight from GD15 to GD182. In PND1, anal atresia and accumulated meconium in the offspring with anorectal malformations. The blind side of the terminal rectum was covered in intestinal epithelium3. Decreased Wnt5a expression in the DBP-exposed group with anorectal malformations. The gene discussed is WNT5A; the disease is anorectal malformation.