Among the former, hypercholesterolaemia (total cholesterol or TC), elevated levels of low-density lipoprotein (LDL-C), low levels of high-density lipoprotein (HDL-C), hypertriglyceridemia and elevated levels of lipoprotein a [Lp(a)] stand out, while among the latter, elevated fasting plasma glucose (FPG), glycated haemoglobin (haemoglobin A1c), fasting insulin (FI) and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) stand out [1,2,3]. The gene discussed is INS; the disease is Insulin resistance.