Deng [47] found that Lycium barbarum polysaccharide (LBP) could reduce intracellular lipid accumulation by inhibiting the endoplasmic reticulum stress IRE1α-XBP1 pathway, and enhancing the function of tumor-associated dendritic cells (TDCs), thereby stimulating the immune function of T cells and exerting anti-tumor effects. The gene discussed is ERN1; the disease is neoplasm.