Interestingly, biantennary galactosylated N-glycan with core fucosylation (A2G2F glycan), which are synthesized by adding terminal residues of β1,4-linked galactose to the β1,2-GlcNAc branches and α1,6-linked fucose to the first GlcNAc residue in the chitobiose core using the enzymes α1,6-fucosyltransferase (FUT8) and N-acetylgalactosaminyltransferases from the B4GALT family, turned out to be elevated in glioblastoma tissue samples and glioma cell lines compared with normal brains. Here, FUT8 is linked to glioblastoma.