PDGFRB and glioblastoma: However, more recently, researchers have found that glioblastoma stem cells have higher levels of ST6GAL1 expression, which was associated with increased proliferation and self-renewal, as confirmed by ST6GAL1 knockdown, which resulted in decreased tumorigenic potential in glioblastoma stem cells via decreased levels of α2,6 sialylation of PDGFRB [41].