FUT8 and neoplasm: Thus, a high level of paucimannosylation in U-87 MG and U-138 MG glioblastoma cell lines with a predominant glycan structure Man3GlcNAc2Fuc, which consists of a naked trimannosyl core and a fucosylated N-acetylglucosamine residue in the chitobiose core and is processed by the enzymes α-mannosidases 2 from the MAN2 family and α1,6- fucosyltransferase FUT8, is associated with proliferation, migration, and invasion of tumor cells [28].