Expression of β1,4-galactosyltransferase V (B4GalT-5), which catalyzes the transfer of β1,4-linked galactose to the β1,6-GlcNAc arm of N-glycans, forming β1,4-Gal-containing N-glycans, suppresses etoposide-induced apoptosis in glioma cells, testifying to its involvement in the development of drug resistance [35]. This evidence concerns the gene B4GALT5 and central nervous system cancer.