Several underlying risk factors or complications during pregnancy were noted, including eclampsia [18], tuberculosis [18,19], systemic lupus erythematosus [19], a prior history of sinus surgery and untreated left upper eyelid swelling [21], agranulocytosis related to autoimmune aplastic anemia [28], and chronic granulomatous disease (autosomal recessive NCF1 [p47phox]–deficient) diagnosed at age nine [30]. Here, NCF1 is linked to systemic lupus erythematosus.