ROS can lead to proliferation and metastasis in various types of cancer through different pathways, including nuclear factor kappa B (NF-κB), extracellular-signal-regulated kinase (ERK), mitogen-activated protein kinase (MAPK), tumor protein p53 (p53), and phosphoinositide 3-kinases (PI3-K) [9,13,14,15]. This evidence concerns the gene TP53 and cancer.