AKT1 and cancer: The mTOR molecule in the mammalian target of rapamycin complex (mTOR) signaling pathway, one of the signaling pathways whose role in cancer is well known, functions primarily as a downstream signaling molecule of the AMP-activated protein kinase (AMPK) pathway, mitogen-activated protein kinase (MAPK) pathway, and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathways and induces cell growth, survival, proliferation, and migration.