SIGLEC9 and neoplasm: The demonstrated associations between SIGLEC9 protein expression and cytokines involved in regulating cell death processes, as well as cytokine and chemokine production, which play a crucial role in shaping the immunosuppressive tumor microenvironment in colorectal cancer, suggest that SIGLEC9 may be considered a promising target for future complex immunotherapeutic approaches in colorectal cancer and other solid tumors, as well as for future clinical studies.