GAD1 and Anxiety: While there is no obvious reason from these data why PCa patients whose cancer is in remission should have more complex GAD networks than PCa patients whose cancer is recurring after treatment or patients whose PCa is undergoing initial treatment, there is ample evidence that many PCa patients do suffer from anxiety of cancer recurrence after treatment and that this anxiety is associated with poorer quality of life, plus more symptoms of mental illness [7,12,13].