MSTN and chronic kidney disease: Specifically, serum myostatin was significantly correlated with vascular reactivity dysfunction (odds ratio [OR] 1.438, 95% confidence interval [CI] 1.057–1.955; p = 0.021) and reduced vascular responsiveness (OR 1.576, 95% CI 1.189–2.089; p = 0.002) in individuals with CKD (Table 2).