The logistic regression analysis showed a greater risk of arrhythmia was associated with interval changes in sST2 [odds ratio (OR): 1.27; 95% CI: 1.03–1.56; P = 0.024] and NT-proBNP (OR: 0.83; 95% CI: 0.70–0.98; P = 0.029). This evidence concerns the gene NPPB and Arrhythmia.