In this study, functional enrichment analysis was performed on the HF-related module (the “Indianred” module identified by WGCNA) and differentially expressed genes, which were enriched in the metabolism-related molecular components and physiological processes such as PPAR signaling, PI3K signaling, ATP generation, and lipid droplet metabolism, revealing that these core genes are closely related to lipid homeostasis and metabolic reprogramming (25, 26). Here, PPARA is linked to hydrops fetalis.