Enrichment analysis revealed that the lipid-associated metabolic process was closely associated with the occurrence of HF including lipid droplets (PLIN2, ACSL4, RAB7A, RAB3GAP1, RAB18, SCCPDH, HSD17B11, and RAB10 were enriched) in the cellular component, PPAR signaling (PLIN2, ACSL1, ACSL4, ILK, and ELOVL5 were enriched) in the pathway component, and transcriptional factor binding (CDKN2A, DDX3X, NR3C1, GTF2I, HIF1A, HMGB2, NAB1, PRKDC, PSMD10, RAD21, TAF7, HIRA, UBE2I, YWHAZ, SUZ12, and MED30 were enriched) in the molecular function component (Figure 3). The gene discussed is RAD21; the disease is hydrops fetalis.