Therefore, we primarily focused on the other four inflammatory factors potentially influenced by heart failure, as detailed below: Artemin (ARTN, OR = 0.856, 95% CI = 0.740–0.989, P = 0.035, PFDR = 0.532); Fibroblast Growth Factor 5 (FGF5, OR = 0.819, 95% CI = 0.713–0.942, P = 0.005, PFDR = 0.398); Matrix Metallopeptidase 10 (MMP-10, OR = 1.165, 95% CI = 1.024–1.326, P = 0.021, PFDR = 0.401); Signaling Lymphocytic Activation Molecule (SLAM, OR = 1.166, 95% CI = 1.021–1.332, P = 0.024, PFDR = 0.401). This evidence concerns the gene FGF5 and heart failure.