In addition to the above-mentioned proteins SYNJ1, TUBB, RHOA, ACTB, and AGO1, we identified another five proteins from the dataset that were dysregulated both in the cellular and extracellular proteome and appeared as promising biomarker candidates based on probable functional relevance and previous appearances in publications related to PD or LRRK2. The gene discussed is AGO1; the disease is Parkinson disease.