The results suggested that a low level of calcium was significantly associated with a high risk of AKI in SAH patients who were aged ≥60 years (OR = 0.27, 95%CI: 0.09–0.83), who had a GCS score of ≥13 (OR = 1.57, 95%CI: 1.08–2.30), who did not use CCB (OR = 2.22, 95%CI: 1.16–4.25) and ACE inhibitors (OR = 1.51, 95%CI: 1.06–2.14), and who did not undergo aneurysm embolization (OR = 1.48, 95%CI: 1.01–2.17) and aneurysm clipping (OR = 1.45, 95%CI: 1.04–2.01). The gene discussed is ACE; the disease is acute kidney injury.