Previous studies have laid great emphasis on the association between EBI3 expression level and the prognosis of specific cancers like breast cancer (Jiang & Liu, 2018), acute myeloid leukemia (Wu et al., 2022) and cervical cancer (Hou et al., 2016), and some experimental analysis have further contributed to the understanding on the participation of EBI3 in colorectal cancer (Liang et al., 2016). Here, EBI3 is linked to colorectal cancer.