In the crude model, total VWF values above the 90th percentile cut-off resulted in an odds ratio (OR) of 4.67 (CI: 1.92-11.3, p<0.001) for APS, and an OR of 5.23 (CI: 2.02-13.5, p<0.001) for non-APS thrombosis. The gene discussed is VWF; the disease is autoimmune polyendocrinopathy.