Another condition associated with thrombocytopenia and the formation of microthrombi in the vasculature is the antiphospholipid syndrome (APS) (8) APS is an auto-immune disease associated with thrombosis and/or recurrent pregnancy loss in combination with the persistent presence of auto-antibodies directed to β2-glycoprotein I (β2GPI), amongst others (7). This evidence concerns the gene APOH and autoimmune polyendocrinopathy.