By blocking CD47, the capacity of CD103+ DCs to take up tumor DNA is increased, thereby promoting the secretion of CXCL9 and IL-12, activating the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, and facilitating the recruitment and activation of NK cells within HCC (166). The gene discussed is ITGAE; the disease is hepatocellular carcinoma.