PPFIBP2 and cholangiocarcinoma: In order to obtain a global view of the genes modulated upon GD3S transfection, we performed a transcriptomic analysis in both iCCA cell lines, selecting the top 1000 up‐ and down‐regulated probes in each CCA cell line (corresponding to 883 and 905 genes in CCLP1 and HUCCT1, respectively) (Figure 6A).