TREM2 and Alzheimer disease: Our previous studies in human induced pluripotent stem cell‐derived microglia (iPS‐Mg) from patients expressing the AD‐linked R47Hhet TREM2 variant and the Nasu Hakola variants T66Mhom and W50Chom increased our understanding of the deficits linked to TREM2 loss‐of‐function (LoF) variants; specifically in aerobic glycolysis and mitochondrial respiration [11, 12, 13].