This new structure of β1-tubulin (encoded by TUBB1), which is the predominant isotype in the marginal band of platelets, will provide insights into β1-tubulin role in diseases such as platelet anisocytosis and congenital thrombocytopenia produced by mutations in TUBB1 (10, 11) but also its potential role in chemotherapy-induced thrombocytopenia in patients under cancer treatment (54). Here, TUBB1 is linked to Congenital thrombocytopenia.