They identified serum PCT levels of 925 pg/mL or more (87% sensitivity, 80.4% specificity, AUC = 0.84) in males and 735 pg/mL or more (77.8% sensitivity, 88.5% specificity, AUC = 0.84) in females as indicators of renal dysfunction in patients with HBV-ACLF [39]. Here, CALCA is linked to Abnormal renal physiology.