The association of the DEPs quantified in this study with hallmarks of cancer, such as remodeling of the tumor microenvironment (e.g., ILK, ITGA4, and SCPEP1), escape of apoptosis (e.g., ILK, GPRC5A, FNTA, and EPB41L3), deregulation of the apical junction and energy metabolism (e.g., ATP6V0A1, KPRP, and ITGA4), and inflammation and immune response processes (e.g., ACAP1 and ITGA4; Fig. 3C), warrants further investigation. The gene discussed is ACAP1; the disease is cancer.