Specially, TGF‐β1 (Shelke et al., 2019; Teixeira et al., 2023; F. Zhang et al., 2023) and one of its cell surface receptors, that is, TβRII receptor (Xie et al., 2022), have been identified as cargo of cancer cell‐derived EVs. This evidence concerns the gene TGFB1 and cancer.