SQSTM1 and viral infectious disease: Catalytically active PLpro enhanced the R-HSPA5-driven oligomerization of SQSTM1/p62 and promoted the selective recruitment of certain components of autophagosome biogenesis machinery while inhibiting the accumulation of lipidated LC3 and impairing reticulophagy, pointing to an important role of the deubiquitinase in the remodeling of ER membranes during viral infection.