Accordingly, we showed in pancreatic cancer cells (KPC) in vitro an induction of monocyte/macrophage-chemoattractant cytokines such as CCL2/MCP1, CCL20/MIP3α, CXCL2/MIP2α and also GM-CSF by Juzentaihoto (and the combination). Here, CSF2 is linked to familial pancreatic carcinoma.