Thuller et al. [29] investigated the relationship between genetic polymorphisms in BMP2 (rs1005464 and rs235768), BMP4 (rs17563), SMAD6 (rs2119261 and rs3934908), and RUNX2 (rs59983488 and rs1200425) with the risk of developing pulp stones. Here, SMAD6 is linked to Pulp calcification.