WES, using a virtual panel for autism and intellectual disability based on human phenotype ontology (HPO) terms and the Simons Foundation Autism Research Initiative (SFARI) database, pointed out several suspected variants, including a homozygous missense variant c.694T>G, p.(Phe232Val) in the EIF3F gene with potentially pathogenic predictions and several variants of uncertain clinical significance (Table 1). The gene discussed is EIF3F; the disease is autism.