EIF3F and Global developmental delay: According to the OMIM database, phenotypic features of the disorder caused by a defect in the EIF3F gene include global developmental delay, mildly to profoundly impaired intellectual development, speech delay or absence, hypotonia, variable facial dysmorphism, and, in some patients, sensorineural hearing defects, microcephaly, sleep disturbances, and autism spectrum disorder [13].